The minimal resolution S also contains a copy of the Poincaré homology sphere, namely π-1(SU(2)/Γ). The reason is that π is an isomorphism away from the singularity.
But this copy of the Poincaré sphere bounds a smooth manifold with boundary, M, since S is smooth!
M ⊂ S
∂M = π-1(SU(2)/Γ)